J-147 CAS 1146963-51-0 Purity ≥99.0% (HPLC) Nootropics In Stock
Ruifu Chemical is the leading manufacturer of J-147 (CAS: 1146963-51-0) with high quality. Ruifu has been supplying pharmaceutical intermediates and fine chemicals more than 15 years.
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Purchase J-147 (CAS: 1146963-51-0), please contact us by e-mail: alvin@ruifuchem.com
| Chemical Name | J-147 |
| Synonyms | J147; CS-1446; N-(2,4-Dimethylphenyl)-2,2,2-trifluoro-N'-(3-methoxybenzylidene)acetohydrazide; (E/Z)-J147; Nootropic J147 |
| Stock Status | In Stock |
| CAS Number | 1146963-51-0 |
| Molecular Formula | C18H17F3N2O2 |
| Molecular Weight | 350.34 g/mol |
| EINECS | 1592732-453-0 |
| Melting Point | 70.0℃~72.0℃ |
| Density | 1.18±0.1 g/cm3 (Predicted) |
| COA & MSDS | Available |
| Origin of Product | Shanghai, China |
| Product Categories |
Pharmaceutical Intermediates |
| Brand | Ruifu Chemical |
| Items | Specifications | Results |
| Appearance | Off-White to Light Yellow Solid | Conforms (By Visual) |
| Odour | Characteristic Odour | Conforms |
| Solubility | Soluble to 100mM in DMSO and to 100mM in ethanol | Conforms |
| Loss on Drying | ≤1.00% | 0.51% |
| Residue on Ignition | ≤0.50% | 0.09% |
| Heavy Metals | ≤20ppm | Conforms |
| Related Substances | Max Single Impurity ≤1.00% | 0.08% |
| Purity / Analysis Method | ≥99.0% (HPLC) | 99.81% |
| Conclusion | The product has been tested and complies with the given specifications | |
Package:Bottle, 10/50/100g/bag, 1kg/bag, or according to customer's requirement.
Storage Condition:Keep the container tightly closed. Store in a cool, dry and well-ventilated warehouse. Keep away from light.
Shipping:Deliver to worldwide by air, by sea, by FedEx / DHL Express. Provide fast and reliable delivery.
J-147 is an exceptionally potent, orally active, neuroprotective agent for cognitive enhancement. J-147 can readily pass the blood brain barrier (BBB). J-147 can inhibit monoamine oxidase B (MAO B) and the dopamine transporter with EC50 values of 1.88 μM and 0.649 μM, respectively. J-147 has potential for the study of Alzheimer’s disease (AD).
J-147 is a novel neurotrophic drug for cognitive enhancement and Alzheimer''s disease. J-147 is an exceptionally potent, orally active and broadly neuroprotective compound has the ability to enhance memory in normal animals as well as to prevent memory deficits in Alzheimer''s disease (AD) transgenic mice. The neurotrophic and memory-enhancing activities of J-147 are associated with an increase in brain derived neurotrophic factor (BDNF) levels and the expression of BDNF responsive proteins, the enhancement of LTP, the preservation of synaptic protein, the reduction of amyloid plaques.
J-147 improves heart health by lowering blood pressure, boosts metabolism, supports digestive and immune system function, improves cognitive function, has no side effects, and increases physical strength with long-term use. Once there is significant weight loss after taking it, this supplement helps people maintain their weight by reducing cravings and increasing energy levels. Since it helps suppress the hunger hormone that causes overeating, people who use J-147 capsules for a long time are more likely to maintain their weight.
J-147 is a potent neurogenic and neuroprotective compound developed for the treatment of neurodegenerative conditions associated with aging.
(1) High purity: J-147 can obtain high-purity products through natural extraction and refining production processes. High purity means better bioavailability and fewer adverse reactions.
(2) Safety: J-147 has been proven to be safe for the human body. Within the dosage range, there are no toxic side effects.
(3) Stability: J-147 has good stability and can maintain its activity and effect under different environments and storage conditions.
(4) Easy to absorb: J-147 can be quickly absorbed by the human body, enters the blood circulation through the intestines, and is distributed to different tissues and organs.
